Sinem Saka

EMBL Heidelberg

European Molecular Biology Laboratory (EMBL), Heidelberg

Group Leader

Sinem Saka received her B.Sc. degree in Molecular Biology and Genetics at Middle East Technical University, Ankara, Turkey in 2008. She earned her PhD in Molecular Biology in 2013 from the University of Goettingen, Germany, where she was a Boehringer Ingelheim Fonds PhD Fellow in the International Max Planck Research School, investigating nanoscale protein organization in cellular membranes with novel super-resolution and multi-modal imaging approaches in the group of Silvio Rizzoli. Sinem then moved to the USA and worked in the group of Peng Yin to develop highly multiplexed imaging techniques as a Human Frontier Science Program (HFSP) Fellow and EMBO postdoctoral fellow at Harvard Medical School and the Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston. In December 2020, she established her independent research group at European Molecular Biology Laboratory (EMBL), Heidelberg, Germany where she is currently a Group Leader and Faculty Member at Genome Biology Unit, with a secondary affiliation to Cell Biology and Biophysics Unit. Her lab focuses on developing and applying new labeling tools for spatial multi-omics and methods to investigate the functional state and spatial and molecular organization of cells across scales and in various diseases. She is a co-inventor of multiple detection methods that utilize DNA nanotechnology, including SABER and Light-Seq technologies.