University of Texas Southwestern Medical Center

Philip O'Bryan Montgomery Jr. Distinguished Chair of Developmental Biology Investigator, Howard Hughes Medical Institute UT Southwestern Medical Center

Helen H. Hobbs is a physician-scientist and Investigator of the Howard Hughes Medical Institute at the University of Texas Southwestern Medical Center (UTSW) in Dallas Texas.  After attending Stanford University and Case Western Reserve Medical School, she trained in internal medicine at Columbia-Presbyterian and UTSW. She joined the faculty of UTSW in 1987 where she is Professor of Internal Medicine and Molecular Genetics. Together with Jonathan C. Cohen, she identified new sequence variations/genes contributing to differences in plasma lipid levels, which led to the development of two new lipid-lowering therapies for the prevention of heart attacks. She also has identified the first and most important genetic difference contributing to susceptibility to fatty liver disease. Gene identification is the starting point for studies to elucidate the pathways and processes that are altered by the defective genes she has identified. She is a member of the National Academy of Medicine, the National Academy of Sciences, and the American Academy of Arts and Sciences.  Among the prizes she has received are the Breakthrough Prize in Life Sciences, the Grand Prix Award from the Institute of France, and the Harrington Prize for Innovation in Medicine.